Endocrine Abstracts

We have recently demonstrated the high potential of non-viral polyplexes for tumor-specific delivery of the sodium iodide symporter (NIS) after systemic application. In the current study we used novel polymers based on linear polyethylenimine (LPEI), shielded by polyethylene glycol (PEG), and coupled with the synthetic peptide B6 (LPEI-PEG-B6) as a transferrin (Tf)-receptor specific ligand to achieve active tumor targeting to human hepatocellular cancer (HuH7) cells after syst...